Scientist, Cell/Molecular Biology
Company: AbbVie
Location: Irvine
Posted on: August 4, 2022
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Job Description:
Individual will develop and execute in vivo models, as well as
perform a range of cell and tissue-based in vitro assays to support
the development and differentiation of implantable biomaterials in
support of Allergan Aesthetics' Medical Device franchises. Under
general supervision and with limited supervisor input, the
candidate will be expected to develop and analyze results tailored
to the in vitro and in vivo evaluation of cell/tissue interactions
with biomaterials. Techniques employed will include intradermal and
subcutaneous injection in small or large animals, 3D imaging,
histology, microscopy, as well as common practices in cell and
molecular biology, such as cell culture, PCR, and ELISA.
Proficiency in in vivo animal handling and care, as well as good
overall working knowledge of common laboratory techniques in a BSL
2 environment is essential. It is also expected that the incumbent
has the ability to successfully perform experiments with routine
troubleshooting, keep accurate records and facilitate
interpretation and analysis of experimental data with the support
of the manager. Additional day to day activities may include
statistical analysis of results, staying current in the relevant
therapeutic areas, and some lab support activities including
ordering materials and general lab organization. The employee must
conduct their work activities in compliance with all AbbVie, Irvine
internal requirements and with all applicable regulatory
requirements, including knowledge of operating in a controlled
environment per the requirements of 21 CFR 820, ISO 13485 and ISO
14971. AbbVie, Irvine internal requirements include compliance with
ethics, environmental health and safety, financial, human
resources, and general business policies, requirements and
objectives. Responsibilities include: Develop and execute in vivo
and in vitro assays to evaluate the tissue response to implantable
biomaterials. Perform studies to develop and qualify new test
methods and procedures. Analysis and interpretation of results,
presentation preparation for internal and external stakeholders.
Document and prepare summaries of results and methods.
Qualifications: A Bachelor's degree in a scientific field (Biology,
Bioengineering, Chemistry or related) plus 4 years post-graduate
experience in industry OR Master with equivalent experience of at
least 2 years. Experience with animal and tissue studies, including
in vivo animal handling/surgeries, in situ, ex vivo and in vitro
models required. Experience using various cell and molecular
biology techniques to examine cell/tissue and biomaterial
interactions. Some experience conducting ex vivo tissue
manipulation for assay performance desirable PDN-ABV2200052
Keywords: AbbVie, Irvine , Scientist, Cell/Molecular Biology, Other , Irvine, California
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