Bioinformatics Scientist II - TIssue Genomics (Remote Option)
Company: Guardant Health
Posted on: January 13, 2022
Guardant Health is a leading precision oncology company focused on
helping conquer cancer globally through use of its proprietary
blood tests, vast data sets and advanced analytics. The Guardant
Health Oncology Platform leverages capabilities to drive commercial
adoption, improve patient clinical outcomes and lower healthcare
costs across all stages of the cancer care continuum. Guardant
Health has launched liquid biopsy-based Guardant360 -, Guardant360
CDx and GuardantOMNI - tests for advanced stage cancer patients.
These tests fuel development of its LUNAR program, which aims to
address the needs of early stage cancer patients with neoadjuvant
and adjuvant treatment selection, cancer survivors with
surveillance, asymptomatic individuals eligible for cancer
screening and individuals at a higher risk for developing cancer
with early detection.
The Bioinformatics Scientist, II will help support the
bioinformatics and technology development teams to maintain and
develop the Guardant360 TissueNext test. As a part of the Tissue
Technology team, you will have the opportunity to innovate and
implement your ideas to constantly improve our product and
analytics so that they are best suited for the changing landscape
of clinical needs. You will part of a tightly integrated team of
wet lab and computational innovators who are dedicated to creating
the best comprehensive genomic profiling solution for all cancer
Essential Duties and Responsibilities:
- Provide analytic support to Tissue Technology Development and
- Work with a variety of Technology Development scientists to
design and analyze development experiments for new platforms and
- Work with members of the bioinformatics group, medical affairs,
and research scientists to conduct relevant analysis regarding
clinical data and the performance of bioinformatics products.
- Explore tissue genomic data from clinical and research samples
and external annotation sources to enhance quality of clinical
- Develop scripts for research and development activities.
- Work together with our collaborators in industry, hospitals and
academia on high-impact translational research using Guardant
Health tests and publish on findings.
- Ph.D. with 1-2 years of relevant experience or M.S. in
bioinformatics or biological sciences 5-7 years relevant
- Knowledge of cancer genomics and tumor biology
- Knowledge of high-throughput sequencing methods
- Experience with Human genetics and Cancer genetics databases
e.g. (ExAC, ClinVar)
- Experience using scripting languages (R, Python or Shell)
- Knowledge of standard bioinformatics tool e.g. SAMtools,
- Working knowledge of statistical methods
- Great communication and presentation skills, ability to present
clearly and effectively to stakeholders across organizations
- Ability to work well in a fast-paced startup environment
- Desire and ability to dig deeply through various data types to
seek out answers
- Strong team player: ability to work together with the team as
well as cross-functionally and even across institutions.
Covid Vaccination Policy: Starting January 7, 2022, Guardant Health
will require all employees to be fully vaccinated to either (a)
establish that they have been fully vaccinated against COVID-19; or
(b) request and obtain an approved exemption from Guardant's
COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as
consistent with applicable laws. An employee is considered fully
vaccinated against COVID-19 two weeks after receiving the second
dose of a two-dose vaccine or one dose of a single-dose
vaccination. Acceptable vaccines are approved or under emergency
use authorization by the U.S. Food and Drug Administration (FDA)
and/or the World Health Organization (WHO). In addition,
fully-vaccinated employees will be required to maintain their
fully-vaccinated status under this policy by obtaining, if
applicable, any FDA-approved boosters.
Employee may be required to lift routine office supplies and use
office equipment. Majority of the work is performed in a
desk/office environment; however, there may be exposure to high
noise levels, fumes, and biohazard material in the laboratory
environment. Ability to sit for extended periods of time.
Guardant Health is an Equal Opportunity Employer. All qualified
applicants will receive consideration for employment without regard
to race, color, religion, sex, sexual orientation, gender identity,
national origin, or protected veteran status and will not be
discriminated against on the basis of disability.
All your information will be kept confidential according to EEO
To learn more about the information collected when you apply for a
position at Guardant Health, Inc. and how it is used, please review
our Privacy Notice for Job Applicants.
Please visit our career page at:
Keywords: Guardant Health, Irvine , Bioinformatics Scientist II - TIssue Genomics (Remote Option), Other , Irvine, California
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